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Aortic Stenosis (sub aorti stenosis) Disease Articles Home |
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Aortic Stenosis (sub aorti stenosis)
About the Diagnosis Cause: The heart is an organ made of muscle cells. When the heart contracts, it pumps oxygenated blood to the body and at the same time it sends "used" unoxygenated blood to the lungs to pick up oxygen. Within the heart are four chambers and four valves to accomplish this task. The four one-way valves ensure that blood always flows in the correct direction. Subaortic stenosis is a narrowing (stenosis) of the area underneath one of these valves, the aortic valve, that causes some degree of obstruction or blockage of the blood flow through the heart. The narrowing can be mild, moderate, or severe; if moderate or severe, it can force the heart to work harder and potentially be harmful to the heart's health. Subaortic stenosis is a problem that affects dogs but not cats. It most commonly occurs in large-breed dogs. Subaortic stenosis appears to be genetic in origin; the first signs of it may be present at birth (moderate or severe cases) or may appear in the first year of life (usually milder cases). The most common clue that subaortic stenosis exists is a heart murmur heard by a veterinarian with a stethoscope; there are many other possible causes of heart murmurs, however, such that tests are necessary to pinpoint the cause of the murmur (see below). In moderate (sometimes) and severe (almost always) cases, symptoms such as weakness, breathing difficulty (dyspnea), fainting (syncope), and, in extreme cases, sudden death are all possible as a result of subaortic stenosis. Diagnosis: Your veterinarian will perform a thorough physical examination (including listening carefully with a stethoscope for a heart murmur or irregular heartbeat) and take a complete history, including asking you about whether you have seen any of the symptoms described above, whether your dog's siblings or parents have been diagnosed with a heart murmur or with subaortic stenosis, whether your dog is receiving medication, and so on. Chest x-rays are useful if symptoms such as labored breathing are present because dogs can develop labored breathing for many reasons, not just subaortic stenosis. Chest x-rays can show the telltale signs, such as fluid accumulation in the lung tissue in severe cases, and help to rule out other problems with similar symptoms. An electrocardiogram (ECG) depicts the pattern of electrical activity in the heart and any irregularities in the heart's rhythm (arrhythmias). An echocardiogram, commonly called cardiac ultrasound, is the test of choice for subaortic stenosis. To perform this exam, a small area of the dog's chest is shaved and an ultrasound probe is gently moved along the skin. An image of the inside of the heart is displayed on a monitor in real time. This test allows the veterinarian to assess the valves (including any narrowing), blood flow patterns and velocity, degree of stenosis (i.e., extent of blockage), and other aspects of cardiac structure and function. Probably the most important functions of the echocardiogram are to confirm or deny that subaortic stenosis is present and, if it is there, to assess its degree of severity. The degree of severity is assessed using several components of the ultrasound exam, especially Doppler ultrasound, which measures the direction and flow of blood as it courses through the heart. Living with the Diagnosis Mild subaortic stenosis is of no consequence to an individual dog, and generally the only intervention is to recommend not breeding. Moderate or severe subaortic stenosis may cause symptoms and may increase the risk of sudden death. Depending on the exact degree of severity, treatment may be required, and other measures (such as limiting activity) may be recommended to minimize the amount of work done by the heart. There is no cure for subaortic stenosis. Since it is thought to be of genetic origin in some breeds such as golden retrievers, boxers, rottweilers, and some others, it is often recommended that dogs with subaortic stenosis not be bred to avoid passing the disease along to future generations. If treatment is necessary, give medication to your dog exactly as directed. Medication may control some symptoms and improve quality of life. As the disease progresses, medication may need to be increased or changed. Understand the possible side effects of all medication being given so that you know what is normal and abnormal. Subaortic stenosis disrupts blood flow in such a way that infection of the heart valves (endocarditis) is more likely to occur than in dogs who do not have subaortic stenosis. Therefore, to decrease the possibility of causing or worsening endocarditis, antibiotics usually are prescribed before any surgical procedures, including prophylactic teeth cleanings, and whenever the risk of blood-borne infection exists (e.g., any wounds). Follow your veterinarian's instructions to limit activity and stressful situations. These can make symptoms worse or even be life-threatening in dogs, especially those with very severe subaortic stenosis. Treatment If the disease is mild, treatment is not required. However, subaortic stenosis can get worse as a growing dog reaches its adult age and body size. Therefore, dogs with moderate or severe subaortic stenosis, whether they have that degree of subaortic stenosis when first detected or whether they "grow into" a more severe form of subaortic stenosis, may require medication. The most common form of treatment is a type of medication given orally (pills) called β-blockers, which reduce the intensity of the heart's work, help to prevent the heart from beating too fast and can control arrhythmias. Several surgical procedures and minimally invasive (balloon catheterization) procedures have been performed to reduce the obstruction of subaortic stenosis. None reliably enhances long-term survival, however, so treatment, when it is necessary, remains focused on medications. DOs
DON'Ts
When to Call Your Veterinarian
Signs to Watch For
Routine Follow-Up
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